欢迎来到上海九游中国实业有限公司网站！
咨询电话：18321818584欢迎来到上海九游中国实业有限公司网站！咨询电话：18321818584
产品分类
Product Category九游中国相关的文章
Related Articles详细介绍
P38相互作用蛋白抗体
产品名称 | 英文名称 | 货号 |
P38相互作用蛋白抗体 | FAM48A | GOY-01K1280 |
商品属性：
英文名称: FAM48A
中文名:P38相互作用蛋白抗体
别 名；SP20H_HUMAN;
Transcription factor SPT20 homolog; p38-interacting protein; p38IP.
研究领域；肿瘤 细胞生物 神经生物学 信号转导 激酶和磷酸酶
抗体来源；Rabbit
克隆类型；Polyclonal
交叉反应；(predicted:
Human, Mouse, Rat, Cow, )
产品应用；ELISA=1:5000-10000
not yet tested in
other applications.
optimal
dilutions/concentrations should be determined by the end user.
理论分子量；86kDa
细胞定位；细胞核
性 状；Liquid
浓 度；1mg/ml
免 疫 原；KLH
conjugated synthetic peptide derived from human FAM48A: 21-120/779
亚 型；IgG
纯化方法；affinity
purified by Protein A
缓 冲 液；0.01M
TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
注意事项；This
product as supplied is intended for research use only, not for use in human,
therapeutic or diagnostic applications.
产品介绍:
FAM48A is a 779 amino acid protein that interacts
with p38 MAP kinase. Specifically, FAM48A and p38 are required for
downregulation of E-cadherin during gastrulation. In adult tissues, FAM48A is
highly expressed in testis and moderately expressed in brain and pituitary
gland. It is also expressed in several fetal tissues, including lung, brain,
thymus and kidney. Expression of FAM48A has been shown to be downregulated in
malignant prostate tissues. The gene encoding FAM48A maps to human chromosome
13, which houses over 400 genes and comprises approximately 4% of the human
genome. Key tumor suppressor genes on chromosome 13 include the breast cancer
susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. Required for MAP kinase p38 (MAPK11, MAPK12,
MAPK13 and/or MAPK14) activation during gastrulation. Required for
down-regulation of E-cadherin during gastrulation by regulating E-cadherin
protein level downstream from NCK-interacting kinase (NIK) and independently
of the regulation of transcription by Fgf signaling and Snail (By
similarity). Required for starvation-induced ATG9A trafficking during
autophagy. |
多克隆抗体制备：
我公司合成抗原，保证阳性血清和抗体ELISA效价达到1：32000，由蛋白抗原制备的多抗，保证WB检测结果是阳性。技术服务实行分步报价，按节点收费，为客户节约成本。
鼠单克隆抗体制备:
客户可根据项目实际需求情况灵活选择进行，我公司将为您的项目提供专业的建议。在制备过程中，与客户互动验证，确保最终制备的抗体ELISA阳性血清检测达到合同要求的同时，也能满足客户抗体最终应用验证需求。技术服务实行分步报价，按节点收费，为客户节约成本。
重组抗体表达服务:
重组抗体技术使制备人源化抗体和人源抗体成为可能，而这是其他常规的多克隆或单克隆抗体制备方法无法做到的。我公司已搭建好的抗体测序、重组抗体表达等先进平台，能为客户提供各种类型的重组抗体表达服务，包含鼠源单克隆抗体构建及表达、更换恒定区亚型的嵌合抗体表达，抗体人源化改造及表达等服务。
单项免疫学及检测服务:
我公司也为客户提供单项免疫学和检测服务，如动物免疫、动物饲养、抗体修饰服务（如FITC，HRP等的标记）、以及ELISA，WB，IHC，DB等检测服务。
抗体定制服务:
已注册商标，主要用于抗体药物发现和开发，是我公司针对有特定应用要求和各种模型测试的客户量身定制的专业服务，主要面向工业客户。
产品咨询
电话
微信扫一扫
联系人：销售部
地址：上海市嘉定区澄浏公路52号
邮箱：3004918891@qq.com
手机：18321818584 / 15026555973